First issue of playing an antagonist is the lag caused by the host severely limiting the antag's gameplay. Lagg should not favor the host in the manner that it affects the antag's respawn timer.
There are instances where the internet is so bad I’ve waited over 10 to 15 seconds to simply respond outside of the 18 sec timer. It makes a huge difference in possibly wining the match or not. If you die when they’re out of lives and I only have 40 secs to kill everyone, but because of the host I have 10 secs or less after a death just due to lag favoring the host.
Second issue is the lives or time to eliminate everyone.The unlimited lives is an issue to winning many instances as an antagonist. 36 lives is more than sufficient for raiders to still have a safe guard, while giving antagonist a realistic chance to win. As shown short fuse is easier maps to win outside of character niches for certain maps or tolchok.
Another solution is making the first time downing everyone 16 times timer at least 60 seconds. Antagonist after the first down do not have enough time in most cases to eliminate 4 people in 45 seconds. This isn't a huge change in terms of math of time per person, but significant enough to be more possible as an antagonist.
Third issue, which i'm sure has been mentioned before is the respawn placements for certain maps are just terrible. Most notibly on Hanging on a thread round 2. I would suggest spawning where ever a person wants, but to a certain part of the map restricted.
Last issue is the scoring part of an antagonist. Most maps you wont really have a chance until the last round or second to last. The issue is scores being largely round based to have a high score. Most maps just guarentee 3rd round because it's that easy like Fistful Sand, Enemy Within, Weapon of the Past, No Reservation, Hanging, all easy for being decent. Kills should weigh more into a persons score if over 36 kills as that takes reasonable effort to down a coordinated team to use 2 aleph refills
(Please keep in mind the focus of these suggestions are to increase possibility of winning and make being a antagonist less frustrating against a system favoring raiders.)